Coordinated AI agents for advancing healthcare (2025)

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Nature Biomedical Engineering (2025)Cite this article

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  • Health care
  • Medical imaging

Decentralized yet coordinated networks of specialized artificial intelligence agents, multi-agent systems for healthcare (MASH), that excel in performing tasks in an assistive or autonomous manner within specific clinical and operational domains are likely to become the next paradigm in medical artificial intelligence.

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Coordinated AI agents for advancing healthcare (1)
Coordinated AI agents for advancing healthcare (2)
Coordinated AI agents for advancing healthcare (3)
Coordinated AI agents for advancing healthcare (4)

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Acknowledgements

We thank R. Reddy for early review and discussion of the figures.

Author information

Authors and Affiliations

  1. Saint Louis University, SSM Health, St. Louis, MO, USA

    Michael Moritz

  2. Scripps Research, La Jolla, CA, USA

    Eric Topol

  3. Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA

    Pranav Rajpurkar

Authors

  1. Michael Moritz

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  2. Eric Topol

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  3. Pranav Rajpurkar

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Contributions

M.M., E.T. and P.R. all contributed to the design, drafting and editing of the manuscript.

Corresponding author

Correspondence to Pranav Rajpurkar.

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The authors declare no competing interests.

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Nature Biomedical Engineering thanks Ahmed Alaa and Vivek Natarajan for their contribution to the peer review of this work.

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Coordinated AI agents for advancing healthcare (5)

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Moritz, M., Topol, E. & Rajpurkar, P. Coordinated AI agents for advancing healthcare. Nat. Biomed. Eng (2025). https://doi.org/10.1038/s41551-025-01363-2

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